Integration of flexible electronics and biomedical engineering is a rapidly growing research area driven by its promising potential to assist personal healthcare, and robotic intelligence. Flexible technology introduces novel devices by merging materials science, device manufacture, and medical application. Over the last decade, flexible and stretchable bioelectronics have already further spearheaded the research development in biological sensing and diagnostic platform, as well the human-machine interactive device. Incorporation of biosensing interface can open up opportunities into noninvasive monitoring human metabolism from sweat, which contains physiologically and metabolically information, and rich robotic sensing capabilities to support the further medical applications like agriculture, security, and public health.